Allegra has the lowest risk of sedation out of all antihistamines so is preferred if an antihistamine is needed for people working in safety-critical jobs. Comparative efficacy of cetirizine and fexofenadine for seasonal allergic rhinitis, hours postdose, in the environmental exposure unit. Side Effects, Interactions and Price Side effects are generally mild with second-generation antihistamines and include a headache and rarely dry mouth, and nausea. More studies are needed to determine if there are any interactions between second generation antihistamines and herbal products and other types of food.
Always speak with your doctor of pharmacist before using any drugs in combination. All the second generation antihistamines currently on the market appear free from adverse cardiovascular effects. Ann Allergy Asthma Immunol.
No difference in side effects was noted between the two. However, the intranasal antihistamine azelastine is effective. Allegra works within two hours and Zyrtec works within one hour. Thin postnasal drip secretions caused by allergies may be treated with antihistamines.
Current Status and Future Directions. In the treatment of post nasal drip caused by nonallergic causes, oral second-generation antihistamines are not very effective. Other treatments include decongestants, cromolyn, and corticosteroid nasal sprays. Second-generation antihistamines such as Allegra and Zyrtec may offer better relief than older-type antihistamines such as promethazine older antihistamines tend to thicken post-nasal secretions.
If thin nasal mucus secretions become thick and turn yellow or green, bacterial infection is likely and a doctor should be seen to obtain antibiotics. Both fexofenadine and cetirizine are popular antihistamines with many similarities but there are some important differences. Cetirizine, the active ingredient of Zyrtec works within one hour.
Studies have not compared the effects of Allegra and Zyrtec for conditions such as postnasal drip, but research suggests intranasal antihistamines such as azelastine are more effective. Allegra fexofenadine and Zyrtec cetirizine are second-generation antihistamines.
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